Apalutamide will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications that are CYP3A4 substrates may end up in lessen exposure to these drugs. Thanks to these adjustments in exercise https://nickg443yoe2.wikistatement.com/user